Easy Med Notes

OSTEOPOROSIS   Osteoporosis is commonest metabolic bone disease.   osteoporosis is characterised by a reduction in the bone density due to a decrease in the bone mass. This occurs when the rate of bone resorption exceeds the rate of bone formation.  CAUSES Several aetiological factors are present. Commonest factor in males is senility and in females is menopause . Causes of generalized osteoporosis : Senility Post-immobilization  example : a bed-ridden patient  Post-menopausal Protein deficiency,  Inadequate intake – old age, illness Malnutrition Malabsorption Excess protein loss (3rd degree burns, CRF etc.)  Endocrine Cushing's disease,  Cushing's syndrome,  Hyperthyroid stat e  Drug induced Long term steroid therapy ,  Phenobarbitone therapy . CLINICAL FEATURES  Osteoporosis is an asymptomatic disorder unless complications predominantly fractures occur.  Loss of bone mass leads to loss of strengt...